2011

Cone photoreceptor degeneration in Leber congenital amaurosis

Zhang T, Zhang N, Baehr W, Fu Y. (2011) Cone opsin determines the time course of cone photoreceptor degeneration in Leber congenital amaurosis. Proc Natl Acad Sci U S A. Epub 2011 May 9.

Mechanism of temperature recognition in Drosophila

Gallio M, Ofstad TA, Macpherson LJ, Wang JW, Zuker CS. (2011) The coding of temperature in the Drosophila brain. Cell. 2011 Feb. 18;144(4):614-24.

Method for preparing stable and functional GPCRs

Corin K, Baaske P, Ravel DB, Song J, Brown E, Wang X, Geissler S, Wienken CJ, Jerabek-Willemsen M, Duhr S, Braun D, Zhang S. (2011) A robust and rapid method of producing soluble, stable, and functional G-protein coupled receptors. PLoS One. 2011;6(10):e23036.

Thompson AA, Liu JJ, Chun E, Wacker D, Wu H, Cherezov V, Stevens RC. (2011) GPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles. Methods. 2011 Oct 21.

Localization and molecular property of mammalian OPN5

Kojima D, Mori S, Torii M, Wada A, Morishita R, Fukada Y. (2011) UV-Sensitive Photoreceptor Protein OPN5 in Humans and Mice. PLoS One. 2011;6(10):e26388.

Nieto PS, Valdez DJ, Acosta-Rodriguez VA, Guido ME. (2011) Expression of Novel Opsins and Intrinsic Light Responses in the Mammalian Retinal Ganglion Cell Line RGC-5. Presence of OPN5 in the Rat Retina. PLoS One. 2011;6(10):e26417.

Change of conformational dynamics of helix 8 of rhodopsin by binding to arrestin

Kirchberg K, Kim TY, Moller M, Skegro D, Dasara Raju G, Granzin J, Buldt G, Schlesinger R, Alexiev U. (2011) Conformational dynamics of helix 8 in the GPCR rhodopsin controls arrestin activation in the desensitization process. Proc Natl Acad Sci U S A. Epub 2011 Oct 28.

Kinetic analysis of thermal reactions of rhodopsin, retinal isomerization and Schiff base hydrolysis

Liu J, Liu MY, Nguyen JB, Bhagat A, Mooney V, Yan EC. (2009) Thermal decay of rhodopsin: role of hydrogen bonds in thermal isomerization of 11-cis retinal in the binding site and hydrolysis of protonated Schiff base. J Am Chem Soc. 2009 Jul 1;131(25):8750-1.

Liu J, Liu MY, Fu L, Zhu GA, Yan EC. (2011) Chemical kinetic analysis of thermal decay of rhodopsin reveals unusual energetics of thermal isomerization and hydrolysis of schiff base. J Biol Chem. 2011 Nov 4;286(44):38408-16.

Expression pattern and function of zebrafish melanopsins

Davies WI, Zheng L, Hughes S, Tamai TK, Turton M, Halford S, Foster RG, Whitmore D, Hankins MW. (2011) Functional diversity of melanopsins and their global expression in the teleost retina. Cell Mol Life Sci. Epub 2011 Aug 11.

Kinetic analysis of interaction between rhodopsin and transducin

Dell'orco D, Koch KW. (2011) A dynamic scaffolding mechanism for rhodopsin and transducin interaction in vertebrate vision. Biochem J. Epub 2011 Aug 15.

Structural analysis of the complex of rhodopsin dimer and transducin

Jastrzebska B, Ringler P, Lodowski DT, Moiseenkova-Bell V, Golczak M, Muller SA, Palczewski K, Engel A. (2011) Rhodopsin-transducin heteropentamer: Three-dimensional structure and biochemical characterization. J Struct Biol. Epub 2011 Sep 6.

The role of Cysteine-rich domain on activation of mGluRs

Huang S, Cao J, Jiang M, Labesse G, Liu J, Pin JP, Rondard P. (2011) Interdomain movements in metabotropic glutamate receptor activation. Proc Natl Acad Sci U S A. Sep 13;108(37):15480-5.

The binding mechanism of miraculin to sweet taste receptor

Koizumi A, Tsuchiya A, Nakajima KI, Ito K, Terada T, Shimizu-Ibuka A, Briand L, Asakura T, Misaka T, Abe K. (2011) Human sweet taste receptor mediates acid-induced sweetness of miraculin. Proc Natl Acad Sci U S A. Epub 2011 Sep 26.

Crystal structure of the β(2) adrenergic receptor-Gs protein complex

Rasmussen SG, Devree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, Thian FS, Chae PS, Pardon E, Calinski D, Mathiesen JM, Shah ST, Lyons JA, Caffrey M, Gellman SH, Steyaert J, Skiniotis G, Weis WI, Sunahara RK, Kobilka BK. (2011) Crystal structure of the β(2) adrenergic receptor-Gs protein complex. Nature Epub 2011 Jul 19.

The protein UNC119 works for trafficking of transducin in rod photoreceptors.

Gopalakrishna KN, Doddapuneni K, Boyd KK, Masuho I, Martemyanov KA, Artemyev NO. (2011) Interaction of transducin with uncoordinated 119 protein (UNC119): implications for the model of transducin trafficking in rod photoreceptors. J Biol Chem. Epub 2011 Jun 28.

Thermal activation of visual pigments involves isomerization of the chromophore.

Luo DG, Yue WW, Ala-Laurila P, Yau KW. (2011) Activation of visual pigments by light and heat. Science. Jun 10;332(6035):1307-12.

An endoproteolysis enzyme, Rce1 is required for trafficking of PDE6 in rod photoreceptor cell

Christiansen JR, Kolandaivelu S, Bergo MO, Ramamurthy V. (2011) RAS-converting enzyme 1-mediated endoproteolysis is required for trafficking of rod phosphodiesterase 6 to photoreceptor outer segments. Proc Natl Acad Sci U S A. May 24;108(21):8862-6. Epub 2011 May 9.

Stoichiometry of arrestin binding depending on the percentage of activated rhodopsin

Sommer ME, Hofmann KP, Heck M. (2011) Arrestin-rhodopsin binding stoichiometry in isolated rod outer segment membranes depends on the percentage of activated receptors. J Biol Chem. Mar 4;286(9):7359-69. Epub 2010 Dec 17.

Functional analysis of dominant-negative mutant of G protein alpha subunit, S43N

Ramachandran S, Cerione RA. (2011) A dominant-negative Galpha mutant that traps a stable rhodopsin-Galpha-GTP-betagamma complex. J Biol Chem. Apr 8;286(14):12702-11. Epub 2011 Feb 1.

Pineal organ regulates background color adaptation of zebrafish

Zhang C, Song Y, Thompson DA, Madonna MA, Millhauser GL, Toro S, Varga Z, Westerfield M, Gamse J, Chen W, Cone RD. (2010) Pineal-specific agouti protein regulates teleost background adaptation. Proc Natl Acad Sci U S A. Nov 23;107(47):20164-71. Epub 2010 Oct 27.

Function of rhodopsin in temperature discrimination in Drosophila

Shen WL, Kwon Y, Adegbola AA, Luo J, Chess A, Montell C. (2011) Function of rhodopsin in temperature discrimination in Drosophila. Science. Epub 2011 Mar 11.

Role of bulk water in the hydrolysis of rhodopsin's chromophore

Jastrzebska B, Palczewski K, Golczak M. (2011) Role of bulk water in the hydrolysis of rhodopsin's chromophore. J Biol Chem. Epub 2011 Apr 1.

Role of Tyr223 in the activation and G-protein interaction of rhodopsin

Elgeti M, Kazmin R, Heck M, Morizumi T, Ritter E, Scheerer P, Ernst OP, Siebert F, Hofmann KP, Bartl FJ. (2011) Conserved tyr223(5.58) plays different roles in the activation and g-protein interaction of rhodopsin. J Am Chem Soc. Epub 2011 Apr 20.

Key residues of arrestins for binding to GPCRs

Vishnivetskiy SA, Gimenez LE, Francis DJ, Hunson SM, Hubbell WL, Klug CS, Gurevich VV. (2011) Few residues within an extensive binding interface drive receptor interaction and determine the specificity of arrestin proteins. J Biol Chem. Epub 2011 Apr 6.

Photoactivation of cryptochrome in Drosophila

Fogle KJ, Parson KG, Dahm NA, Holmes TC. (2011) CRYPTOCHROME is a blue-light sensor that regulates neuronal firing rate. Science. 2011 Mar 18;331(6023):1409-13. Epub 2011 Mar 3.

Crystal structure of metarhodopsin II

Choe HW, Kim YJ, Park JH, Morizumi T, Pai EF, Kraus N, Hofmann KP, Scheerer P, Ernst OP. (2011) Crystal structure of metarhodopsin II. Nature. 2011 Mar 31;471(7340):651-655. Epub 2011 Mar 9.

Standfuss J, Edwards PC, D'Antona A, Fransen M, Xie G, Oprian DD, Schertler GF. (2011) The structural basis of agonist-induced activation in constitutively active rhodopsin. Nature. 2011 Mar 31;471(7340):656-60. Epub 2011 Mar 9.