perpers

分子生体情報学分科の研究業績

論文として公表したもののリストアップです。

それぞれの論文は文献のデータベースであるPubMedへリンクされています。興味のある方はPubMedのリンクから論文をダウンロードする事が出来ます。

以前に公表された論文はこちらから

2021-2025  /  2016-2020  /  2011-2015  /  2006-2010  /  

2001-2005  /  

2020

Rhodopsin-mediated light-off-induced protein kinase A activation in mouse rod photoreceptor cells
Sato S, Yamashita T, Matsuda M.
Proc Natl Acad Sci U S A. 2020 Oct 12;202009164. doi: 10.1073/pnas.2009164117.
プレスリリース
Rapid Oxidation Following Photoreduction in the Avian Cryptochrome4 Photocycle
Otsuka H, Mitsui H, Miura K, Okano K, Imamoto Y, Okano T.
Biochemistry. 2020 Sep 29;59(38):3615-3625. doi: 10.1021/acs.biochem.0c00495.
Dark noise and retinal degeneration from D190N-rhodopsin
Daniel Silverman,Zuying Chai,Wendy W S Yue,Sravani Keerthi Ramisetty,Sowmya Bekshe Lokappa,Kazumi Sakai,Rikard Frederiksen,Parinaz Bina,Stephen H Tsang,Takahiro Yamashita,Jeannie Chen,King-Wai Yau
Proc Natl Acad Sci U S A. 2020 Sep 15;117(37):23033-23043. doi: 10.1073/pnas.2010417117.
Regulation of Photocycle Kinetics of Photoactive Yellow Protein by Modulating Flexibility of the β-Turn
Yasushi Imamoto, Hiroaki Sasayama, Miki Harigai, Yuji Furutani, Mikio Kataoka
J Phys Chem B.2020 Feb 27;124(8):1452-1459. doi: 10.1021/acs.jpcb.9b11879.
Synthesis of One Double Bond-Inserted Retinal Analogs and Their Binding Experiments with Opsins: Preparation of Novel Red-Shifted Channelrhodopsin Variants.
Takashi Okitsu, Yumiko Yamano, Yi-Chung Shen, Toshikazu Sasaki, Yuka Kobayashi, Shoko Morisawa, Takahiro Yamashita, Yasushi Imamoto, Yoshinori Shichida, Akimori Wada
Chem Pharm Bull2020;68(3):265-272. doi: 10.1248/cpb.c19-01005.

Reviews and Other Publications

C. Fujiyabu, T. Yamashita (2020) Retroduplication of rhodopsin gene 400 million years ago diversified the photoreception in fishes. Atlas of Science.
T. Yamashita (2020) Unexpected molecular diversity of vertebrate non-visual opsin Opn5.Biophys. Rev., 12, 333-338.
山下 高廣(2020)「カエルは暗がりでも色が見分けられる！？」 ＡＦＴジャーナル（色彩検定協会）vol.72

 

2019

Conformational Differences among Metarhodopsin I, Metarhodopsin II, and Opsin Probed by Wide-Angle X-ray Scattering.
Imamoto Y, Kojima K, Oka T, Maeda R, Shichida Y.
J Phys Chem B. 2019 Oct 31;123(43):9134-9142. doi: 10.1021/acs.jpcb.9b08311.
Evolutionary history of teleost intron-containing and intron-less rhodopsin genes.
Fujiyabu C, Sato K, Utari NML, Ohuchi H, Shichida Y, Yamashita T.
Sci Rep.2019 Jul 23;9(1):10653. doi: 10.1038/s41598-019-47028-4.
Elementary response triggered by transducin in retinal rods.
Yue WWS, Silverman D, Ren X, Frederiksen R, Sakai K, Yamashita T, Shichida Y, Cornwall MC, Chen J, Yau KW.
Proc Natl Acad Sci U S A. 2019 Feb 22. pii: 201817781. doi: 10.1073/pnas.1817781116.

Reviews and Other Publications

佐藤恵太、山下高廣、大内淑代、七田芳則 (2019) 「光受容体」Opn5が示す多様な分子機能」生物物理 59, 132-6.

 

2018

Pinopsin evolved as the ancestral dim-light visual opsin in vertebrates.
Sato K, Yamashita T, Kojima K, Sakai K, Matsutani Y, Yanagawa M, Yamano Y, Wada A, Iwabe N, Ohuchi H, Shichida Y.
Commun Biol. 2018 Oct 1;1:156. doi: 10.1038/s42003-018-0164-x.
プレスリリース
Single-molecule diffusion-based estimation of ligand effects on G protein-coupled receptors.
Yanagawa M, Hiroshima M, Togashi Y, Abe M, Yamashita T, Shichida Y, Murata M, Ueda M, Sako Y.
Sci Signal. 2018 Sep 18;11(548). pii: eaao1917. doi: 10.1126/scisignal.aao1917.
プレスリリース
Red-Tuning of Channelrhodopsin Spectrum Using Long-Conjugated Retinal Analogues.
Shen YC, Sasaki T, Matsuyama T, Yamashita T, Shichida Y, Okitsu T, Yamano Y, Wada A, Ishizuka T, Yawo H, Imamoto Y.
Biochemistry. 2018 Aug 28. doi: 10.1021/acs.biochem.8b00583.
Genotype determination of the OPN1LW/OPN1MW genes: novel disease-causing mechanisms in Japanese patients with blue cone monochromacy.
Katagiri S, Iwasa M, Hayashi T, Hosono K, Yamashita T, Kuniyoshi K, Ueno S, Kondo M, Ueyama H, Ogita H, Shichida Y, Inagaki H, Kurahashi H, Kondo H, Ohji M, Hotta Y, Nakano T.
Sci Rep. 2018 Jul 31;8(1):11507. doi: 10.1038/s41598-018-29891-9.
Shift in Conformational Equilibrium Induces Constitutive Activity of G-Protein-Coupled Receptor, Rhodopsin.
Maeda R, Hiroshima M, Yamashita T, Wada A, Sako Y, Shichida Y, Imamoto Y.
J Phys Chem B. 2018 May 10;122(18):4838-4843. doi: 10.1021/acs.jpcb.8b02819. Epub 2018 Apr 27.
Opn5L1 is a retinal receptor that behaves as a reverse and self-regenerating photoreceptor.
Sato K, Yamashita T, Ohuchi H, Takeuchi A, Gotoh H, Ono K, Mizuno M, Mizutani Y, Tomonari S, Sakai K, Imamoto Y, Wada A, Shichida Y.
Nat Commun. 2018 Mar 28;9(1):1255. doi: 10.1038/s41467-018-03603-3.
プレスリリース

Reviews and Other Publications

小島 慧一(現岡山大学)(2018)ホヤの光受容タンパク質から眼の進化を追う JT生命誌研究館　生命誌ジャーナル97号
山下高廣、佐藤恵太、七田芳則 (2018)「視覚進化の新モデル –哺乳類が失った“ピノプシン”からたどる脊椎動物の暗所視と色覚」 webメディア「academist Journal」研究紹介コラム

 

2017

Spontaneous Activation of Visual Pigments in Relation to Openness/Closedness of Chromophore-Binding Pocket
Wendy Wing Sze Yue, Rikard Frederiksen, Xiaozhi Ren, Dong-Gen Luo, Takahiro Yamashita, Yoshinori Shichida, M Carter Cornwall, King-Wai Yau
Elife2017 Feb 10; doi:10.7554/eLife.18492
Chimeric microbial rhodopsins for optical activation of Gs-proteins.
Yoshida K, Yamashita T, Sasaki K, Inoue K, Shichida Y, Kandori H.
Biophys Physicobiol. 2017 Dec 19;14:183-190. doi: 10.2142/biophysico.14.0_183. eCollection 2017.
Drosophila melanogaster rhodopsin Rh7 is a UV-to-visible light sensor with an extraordinarily broad absorption spectrum.
Sakai K, Tsutsui K, Yamashita T, Iwabe N, Takahashi K, Wada A, Shichida Y.
Sci Rep. 2017 Aug 4;7(1):7349. doi: 10.1038/s41598-017-07461-9.
プレスリリース
Evolutionary steps involving counterion displacement in a tunicate opsin.
Kojima K, Yamashita T, Imamoto Y, Kusakabe TG, Tsuda M, Shichida Y.
Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):6028-6033.
プレスリリース
Adaptation of cone pigments found in green rods for scotopic vision through a single amino acid mutation.
Kojima K, Matsutani Y, Yamashita T, Yanagawa M, Imamoto Y, Yamano Y, Wada A, Hisatomi O, Nishikawa K, Sakurai K, Shichida Y.
Proc Natl Acad Sci U S A. 2017 May 23;114(21):5437-5442.
プレスリリース
Alternative Formation of Red-Shifted Channelrhodopsins: Noncovalent Incorporation with Retinal-Based Enamine-Type Schiff Bases and Mutated Channelopsin.
Okitsu T, Matsuyama T, Yamashita T, Ishizuka T, Yawo H, Imamoto Y, Shichida Y, Wada A.
Chem Pharm Bull. 2017 Nov 65(4):356-358.

 

2016

Two Opsin 3-Related Proteins in the Chicken Retina and Brain: A TMT-Type Opsin 3 Is a Blue-Light Sensor in Retinal Horizontal Cells, Hypothalamus, and Cerebellum
Kato M, Sugiyama T, Sakai K, Yamashita T, Fujita H, Sato K, Tomonari S, Shichida Y, Ohuchi H
PLoS One. 2016 Nov 18;11(11):e0163925.
Two UV-Sensitive Photoreceptor Proteins, Opn5m and Opn5m2 in Ray-Finned Fish with Distinct Molecular Properties and Broad Distribution in the Retina and Brain
Sato K, Yamashita T, Haruki Y, Ohuchi H, Kinoshita M, Shichida Y
PLoS One. 2016 May 11;11(5):e0155339.